After a mean duration of 5 (1.0) years, 3 cases of pump dysfunction and 3 cases of (expected) battery end-of-life necessitated replacement of the pump.
The development of rash necessitated discontinuation of TVR in 6% and of the entire regimen in 1% of the cases.
However, the variation in designs, used measures and analyses, and the scarcity of reported information that allowed straightforward computation of effect sizes, eventually necessitated examination of all original texts by one of the authors (GJP).
A lack of private sector data on all cadres, particularly ophthalmologists and refractionists, necessitated exclusion of South Africa, one of the more populous countries in the region, from this study.
The primary Siluro-Devonian radiation of terrestrial plants necessitated development of physiological mechanisms that would allow pioneering plants to take advantage of new ecological niches on land.
Presence of insertion/deletion polymorphisms necessitated cloning of individual haplotypes to obtain reliable sequence reads.
The high IC50 values observed with tea and the complex composition of the same necessitated examination of the interactions among fewer metabolites.
Lack of radial pulses and a cold, pale hand after closed reduction and percutaneous pinning of supracondylar fractures necessitated exploration of the cubital fossa [ 18, 19].
The emergence of multiscale design of materials and products has necessitated development of inductive robust design methods to rapidly develop and deploy new material systems.
The analytical determination of each mixture concentration often necessitated adjustments of the nominal mixture ratios, with relative proportions, p i, of the compounds being different for each measured mixture exposure.
Bias might also have been introduced by missing values, which were numerous in the routine data provided by our 18 care groups and necessitated exclusion of 28 to 44% of patients across the four outcome-specific analyses.
