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These are the circumstances that necessitate, at a minimum, a coherent national framework of rules.
As a guide to intuition, our 3-species blocks necessitate at minimum 9 conserved GC's in a 40 bp block to give a p-value of 10-6 or better, though the number of conserved AT bases is also important.
Moreover, clear diagnosis usually necessitates, at minimum, surgical intervention in the form of laparotomy or laparoscopy.
Contact with mucosal surfaces in the body necessitates a minimum of HLD.
The provided standards for kinetic data necessitate a minimum quality of biochemical protein data (e.g enzyme activity provided in µmol product made by µmol enzyme per minute).
It was decided by a run-out review off the final delivery that necessitated at least 20 replays.
And, such an operation would invariably necessitate at least a limited number of U.S. support troops on the ground.
This does not mean that all SIAs are "terrorists," but rather that the travel and behavior of such individuals indicates a possible nexus to nefarious activity (including terrorism) and, at a minimum, provides indicators that necessitate heightened screening and further investigation.
The army interference is at a minimum.
At a minimum, a bit of shelter.
At a minimum, that ensures true competition.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com