Low cell yields associated with the use of biopsies and high stringency cell sorting, necessitated working with 1 ng starting RNA, and hence required rigorous laboratory and bioinformatic procedures to generate reliable microarray data (see online supplementary figure. S1G,H).
Plus he argues that the national constraints of operators help bolster Teralytics against shifts in individual partners' business decisions — by positioning the business to have additional potential data providers standing by as the nature of the telecoms market necessitates it working with "many operators across different markets".
The law includes the confidential handling of patient information, so it necessitates always working with patient records and personal information from secured connections.
This will necessitate meaningful collaboration between the sectors – working with, rather than against, private enterprises.
Different skills are required for each practice, and working with larger groups necessitates a proper channel of communication.
He felt that working with a small team necessitated having a defined vision for the game from the outset, "to answer those first questions about what you want your game to be".
For many studies the design and sampling technique will be dictated by individual research goals, however the unique set of challenges encountered when working with hidden or hard to reach populations, such as refugee groups, necessitates a more pragmatic approach.
When we began working with tephritid genomes, we viewed their large size as an annoyance that necessitated the screening of an unusually large (compared to Drosophila) number of clones to identify genes of interest.
When working with model organisms, GWAS is often performed with the use of populations in which individuals are closely related to one another, necessitating a method to estimate the relatedness.
The scale of the data we work with necessitates a parallel approach, prohibiting us from making all the communication steps required by a traditional coordinate descent method.
