The inability to distinguish the MVA-BAC clones by restriction map, viral growth yield or murine immunogenicity suggests that they are likely to be identical, but the possibility of some bias in the isolation procedure necessitates verification of clone fidelity by complete sequencing, especially prior to embarking on a programme of genetic manipulation.
Having a non-English speaking individual draft the article in their native language with the aid of a professional translator might prove burdensome because of the substantial translation costs, and would also necessitate the verification of the translated text by a native English speaker to ensure its accuracy.
However, it is our view that consideration of any qualitative property, such as morphology of crystals formed from solvents, necessitates additional experimental verification steps.
Furthermore, implementing this process will inevitably lead to lowered ownership thresholds for some customers, necessitating the collection and verification of additional ownership information.
This promising possibility, however, necessitates the need to confirm their scientific verification before use.
The construction of whole genome arrays necessitates the development of high throughput methods suitable for verification of AFPs prior to spotting arrays.
Study of the various functional components in communication-based train control (CBTC) system necessitates a good structural design followed by its validation and verification through a formal modelling technique.
Thus, depending on the security verification pattern required by a service provider (see Figure 5), one subject request can necessitate three different request types with differently sized response data payloads to be made by a service provider to the security provider.
These issues are particularly problematic during verification and validation phases when a system fails to meet a particular requirement, which necessitates a design change.
This necessitates that on one hand, the requirements are specified formally and on the other hand an exhaustive verification is performed.
During the data verification process, irregularities in data collection were identified in one location, Multan, and rectified, which necessitated discarding the original (fraudulent) data and repeating the survey in this location (a full account of this has been published elsewhere [19]).
