Sentence examples for necessitate substantial from inspiring English sources

Law Enforcement Assistance 8. (SBU) Pakistan's terrorism threats necessitate substantial strengthening of the country's law enforcement capabilities.

In most cases, the methodologies developed at the research bench necessitate substantial modifications to reach the criteria needed for industrial implementation.

The construction and implementation of such a national framework will necessitate substantial research and strategic planning to form a coherent theory and systematic practice of English language education specific to the Chinese context.

Since these classical tissue engineering technologies necessitate substantial infrastructure and logistics, we recently introduced decellularized TEHVs (dTEHVs), based on biodegradable synthetic materials and vascular-derived cells, and successfully created a potential off-the-shelf starter matrix for guided tissue regeneration.

But such an endeavour would also necessitate substantial outside funding.

On the whole, the results have not revealed any clear genetic risk factors that would necessitate substantial changes in lifestyle or medical management.

There is an urgent need for a cost-effective, broad-spectrum HPV prophylactic vaccine in developing countries, which necessitates substantial cost subsidization of the virus-like particle (VLP) based vaccines licensed in industrialized countries or an alternative approach with second-generation vaccines that are specifically designed for delivery to women in resource-poor communities.

To be fully effective, such a method necessitates substantial information on vector ecology, distribution of breeding sites and local environmental conditions and should be combined with insecticidal adult vector control [100].

Structural reforms introduced fees for service, necessitating substantial out-of-pocket payments.

The rapidly evolving nature of the research to policy interface within low-income country settings necessitates substantial use of novel approaches to respond to this evolution.

One source of errors that necessitated substantial trimming of the data was homopolymer stretches that pose well-known problems when sequencing with the 454 Roche technology [ 12, 37, 38].