Cops-1 shows a strong bias in codon preference necessitating specialised strains of E. coli for expression of recombinant protein.
Six of the 9 patients with AE complained of constipation necessitating excessive straining over a long period to evacuate the bowel.
He gave us despairing snapshots of men who found themselves on the outskirts of civilian society — a pair of soldiers tasked with notifying the bereaved, a dirty cop, a homeless man on the verge of fading away — and asked us to consider the world that had necessitated their particular strain of torment.
Thus there is a possibility of cross transmission of bTB at wildlife-livestock interface areas that necessitates use of genetic strain typing methods to characterize them accurately.
The large amount of data being obtained for clf genes and the observed importance of these genes in the classification of strains necessitates the transfer and continuity of genetic data between laboratories.
Moreover, there are inherent problems with drug interactions, toxicities, and increasingly reported resistant strains necessitating the urgent identification and characterization of novel targets against A. fumigatus.
The outburst of drug resistant microbial strains necessitates the studies for synergistic effects of antibiotics in combination with plant's derivatives to develop the antimicrobial cocktail with a wider spectrum of activity and reduction of adverse side effects of antimicrobial agents.
The resurgence of tuberculosis and the emergence of multidrug-resistance strains of mycobacteria, necessitate the search for new class of antimycobacterial agents.
Autophagic bodies are rapidly degraded in wild-type cells upon entry into the vacuole, thus necessitating a vacuolar proteinase-deficient strain (such as a pep4 mutant) to visualize them (Takeshige et al. 1992).
While first-line antibiotics are sufficient to ensure a successful treatment of most patients infected with drug susceptible Mycobacterium tuberculosis strains, infections caused by so-called multiresistant (MDR) strains, defined as strains resistant to rifampin and isoniazid, necessitate the use of second-line antibiotics.
This variability is a problem when designing vaccines against this disease, because it necessitates a close match between vaccine strain and virus in an outbreak.
