It is probable that courtship studies under more natural and complex situations than those used here will provide a much more detailed picture of male courtship behavior and hence necessitate modification of the model.
Our results suggest that the use of statins for anticancer therapy may necessitate modification of the formulation and optimising the dose.
2, 3 The latter changes can significantly impair the patients' health-related quality of life, impact activities of daily living, and sometimes necessitate modification or discontinuation of anticancer treatment.
Apart from its theoretical interest, the question is of some practical importance, for alterations in the absorption spectrum due to this cause Would necessitate modifications in the estimation of blood methæmoglobin made by optical methods, for example, that of Evelyn and Malloy3.
New knowledge will necessitate modifications of the classification, and this system has the flexibility to accommodate most foreseeable revisions.
However, the increasing evidence that phenotypic variations exist among isolates in this serogroup may eventually necessitate modifications in assay procedures to detect them.
In addition, many patients with Gouty Arthritis have underlying comorbidities such as cardiovascular disease, diabetes mellitus, hypertension, liver and renal disease, or gastrointestinal problems, which restrict treatment options or necessitate modifications in the management of Gouty Arthritis [ 8, 11- 14].
Three collapses that occurred at initial 800 m length of southern tunnel necessitated modification of either or both of the support system or excavation sequences.
However, the study is being repeated to optimize the rate of drug elution, and multiple stent fractures seen in the first phase of the study necessitated modification of stent design.
The development of the experimental design began with the framework traditionally used for testing field analytical monitoring technologies under the SITE MMT Program, but various unique aspects of the participating technologies and the expected applications for these technologies necessitated modification of several elements of the traditional design.
The high draw-gear (the link between locomotive and tender) of the N class tenders necessitated modification to the frames beneath the cab.
