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Further development and validation of the in silico approaches would necessitate identification of specific compounds and protocols required to establish the predictive power of the simulations to meet the standards of the requirements of regulators and industrial partners.
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RNA targeting through small molecules is an emerging and promising therapeutic route that necessitates identification of small molecules that can selectively target specific RNA structures.
The case study takes its starting point in the perspective of an actor considering how to develop vehicle maintenance services for its customers and points at the need to enable understanding of the conditions for vehicle maintenance, which necessitates identification and analysis of the variety across transport service settings.
Accomplishment of a successful recruitment necessitates identification of the appropriate reef patch and a suitable microhabitat within this patch.
This necessitates identification of not only the function of individual proteins, but also to validate the physical interactions and biological processes in which they participate.
Global spread of MDR TB necessitates identification of treatment options with acceptable safety and tolerability for persons infected with drug-resistant strains.
The rapid changes in today's socio-economic and technological environment in which the enterprises operate necessitate the identification of new requirements that address both theoretical and practical aspects of the Enterprise Information Systems EISS).
The magnitude of relative risk it conferred in this sample, and the substantial proportion in the population at large, necessitate the identification of potential "hyperfiltrators" in the community which has both methodological and clinical implications.
Experiments that require a certain sex ratio necessitate the identification of specific breeding pairs that have been tested earlier and were shown to produce the desired proportion of males/females in their offspring.
These and other clearly demonstrated cases necessitate the identification of specific windows of vulnerability and this poses considerable challenges to established toxicity testing paradigms, all of which Dietrich et al. [ 5] ignore.
This will necessitate an identification of which health needs are best met by each practice model and a comparison of health outcomes and costs associated with different practice models for similar patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com