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While human inhibitor compounds may already possess the desired potency, toxicity, and physicochemical properties for new parasitic agents (and thus be directly repurposed), it is more likely that these compounds' properties will necessitate further optimization to become effective antiparasitic agents.
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There are a few indirect genotyping techniques that have been widely used to date; although these methods require extensive initial optimization, often necessitate further characterization via cloning and sequencing, and are still insufficient when genotyping complex multilocus systems (reviewed in [ 27, 28]).
This will necessitate further in-depth analyses.
Further optimization is required.
These findings necessitate further investigation with hysteroscopy to confirm and possibly treat the pathology [1].
Moreover, interactions with other units within the technical environment necessitate further human relations, as well.
Atypical findings are those that necessitate further investigation by anti-doping authorities.
This would require a further optimization.
Work on 4S this year includes looks at hardware options, Mortari said, and further optimization of the idea.
Answering this question will necessitate further analyses.
Further optimization for adult mouse retinas might be required.
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