Sentence examples for necessitate extended from inspiring English sources

Probes derived from this region did not generate background, though the small size did necessitate extended staining times (up to 5 days).

This may necessitate extended ex vivo culture and/or multiple rounds of T cell activation in order to generate therapeutic levels of Tregs.

A detailed study of these adjuvant treatments would necessitate extending the study population to patients treated after 1999.

And from the technical point of view, the tumor occupied the entire caudate lobe and covered the hilar plate, subsequently protruding outwards and occupying the anterior superior segment of the right liver and stretching to the right hepatic vein, thus necessitating extended left hepatectomy with resection of the RHV.

22 Access to the clivus has traditionally necessitated extended lateral, posterolateral, and anterior surgical approaches.

An example of a Repetition is inadequate exposure, which causes insufficient progress and necessitates extending the incision, or repositioning the retractors.

The design of the FBAT necessitates that extended pedigrees are split into nuclear families, which can introduce bias due to correlation.

One such contemporary defender, the Christian philosopher Paul Helm, has argued that God's loving nature no more necessitates that he extend his redemptive love equally to all humans than it necessitates that he create them all with the same human characteristics.

There were two consuls, who not only controlled the treasury and held supreme authority in government but also led troops, necessitating their absence from Rome for extended periods.

This indicates that the change in the Lys170 conformation, from fully extended to retracted, is necessitated by the proximity of the bound ligand.

These unique characteristics necessitate multidrug therapy, typically ≥4 antibiotics, and extended periods of dosing (6 12 months).