Sentence examples for necessitate determination from inspiring English sources

The dominant and varied influences of HLA polymorphism on the incidence of disease and its treatment necessitate determination of complete, accurate sequences of entire HLA haplotypes, encompassing all HLA class I and II genes and representing human populations worldwide.

This necessitates determination of soil electrical resistivity and thermal resistivity and development of a relationship between them.

Nevertheless, they necessitate the determination of a parameter; the difficulty is to calculate an appropriate value of this regularization parameter.

Eventually, future clinical applications of gene transfer vectors will necessitate accurate determination of expression levels of any therapeutic transgene.

Existence of a threshold concentration for disease incidence, or a strongly nonlinear disease-to-intake response, would necessitate accurate determination of the shape of the population intake distribution.

9, 10 A priori application of these type I-like biomarkers does not necessitate the determination of the biomarker constituent identities since the pattern or signature alone denotes the specific biological activity.

The electrical characterization of a Schottky diode necessitates the determination of the barrier height and the ideality factor.

The design of seismic resistant concrete gravity dam necessitates accurate determination of hydrodynamic pressure developed in the adjacent reservoir.

Understanding neurite outgrowth necessitates quantitative determination of the role of molecular gradients on growth cone navigation under dynamic physiological conditions.

This necessitates precise determination of these resistivities, and relationship between them, which mainly depend on the soil type, its origin, compaction density and saturation.

The fitting of models to data necessitates the determination of parameters describing processes of the biological system [13] [15].