Their resources--allocated space and access to necessary equipment--should be defined clearly.
If deemed necessary, monotonicity constraints were defined to enforce plausible patterns.
To carry out these program assessments, it is necessary to define what is important to measure and how to do it (Portis, 2013).
More investigations are necessary to clearly defined its roles in human obesity.
We performed additional experiments showing that pilus retraction was necessary to form defined colony morphotypes.
Further effort will be necessary to define what this mechanism is but one possibility is that it involves interactions between SIRT1 and other apoptosis-regulatory proteins.
Further studies are necessary to define whether they are the direct and/or indirect downstream targets of SlCaM2.
More studies are necessary to define whether TMS can be an adjuvant tool to stratify patients for specific therapeutic strategies.
It is necessary to define if the recruitment is in weight or in number and if the recruitment is to the fishing area or to the exploited phase.
It was necessary to first define severity of psoriasis before treatment goals were set.
