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Proposals issued by regulators in January "lacked the necessary specificity that we need to understand how this process is going to unfold," Senator Pat Toomey, a Pennsylvania Republican, said at the hearing.
This assay also provided the necessary specificity tests prior to the probes being adapted to an automated biosensor using a sandwich hybridization format.
A possible explanation for this could be deficient homing of cells with necessary specificity to the tumor site [32].
However, a factor found in cell lysates, G-actin, can provide the necessary specificity.
However, none of these have progressed sufficiently to provide the necessary specificity and sensitivity required for clinical implementation.
In these instruments the necessary specificity of the drug imaging experiment can be reached by measuring the precise mass of the drug.
Similar(42)
Salmonella attack of Arabidopsis plants also results in the activation of MPK3 and MPK6 with a similar kinetics (Fig. 1i), showing a transient activation maximum at 15 min. Since MPK3 and MPK6 are implicated in various pathways, the respective signalling complexes rather than the MAP kinases themselves, are thought to provide the necessary signalling specificity.
To achieve necessary sequence specificity, ligamers need to be 40 60 nt.
Interestingly, transient expression of the RBCS3A construct showed no difference in expression of GUS between leaves and green fruit, implying that integration is necessary for specificity.
However, many actin regulators are predicted to be soluble, diffusible proteins, which appear poorly suited to operate with the necessary spatial specificity.
RNAi is the central key of epigenetic control, as it confers the necessary sequence specificity, and exists in different versions within and between species.
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