Although effective even at extremely low concentrations, some LPS was necessary for sensitization because mice receiving OVA with no LPS failed to become sensitized, as judged by their lack of allergic responses to subsequent OVA challenge.
The fact that TRPV1 is necessary for sensitization, but not for the transduction of noxious heat by nociceptors, is an important fact that requires further investigation (Woodbury et al., 2004; Koerber et al., 2010).
Until now, TTC risk assessment models have excluded proteins because the threshold for exposure to food allergens necessary for sensitization and/or elicitation of a response is in most cases unknown.
Asked whether they thought it was necessary, after community sensitization, to take up precautionary measures to cope with floods, they responded: The government must bring relief for them to dig channels or build dykes near their houses.
A KII with chiefs to find out if it was necessary, after community sensitization, to take up precautionary measures to cope with floods reveals: The government must bring relief for them to dig channels or build dykes near their houses.
These results suggest that activation of α2-containing GABAA-Rs in the nucleus accumbens is sufficient and necessary for behavioral sensitization.
The antimetastatic effect of C. parvum appears to be mediated through macrophages in concert with a subpopulation of T lymphocytes, which were considered to be necessary in the sensitization arm of the response as opposed to the effector arm of this response.
Considering that repeated exposure to psychostimulants is not necessary for development of sensitization, since a single exposure is sufficient to induce persistent locomotor sensitization and neurochemical changes, in this study we used the two-injection protocol of amphetamine.
We demonstrate that AMs are necessary to regulate mucosal sensitization to inhaled allergen.
Therefore, both continuous Ca2+ influx and Ca2+-dependent Ca2+ sensitization are necessary to maintain contraction, whereby Ca2+ influx occurs independently from Ca2+ sensitization, but not vice versa.
