One of the most recent antiques success stories, it had the necessary prerequisites: proximity to a place with lots of potential customers (Manhattan a bit more than two hours away) and a depressed downtown with vacant storefronts (meaning cheap rents).
In this respect, an interaction between S1P3 and SR-BI to induce HDL signalling in endothelial cells has been suggested in which binding of HDL with SR-BI could provide the necessary spatial proximity for lysophospholipids to effectively stimulate S1P3 (Nofer et al, 2004).
Aranguren et al. (2010) also highlight the importance of active learning process called "complicit knowledge" (ibid:49), revealing its uncodified nature and the proximity necessary to acquire it.
Aggregative behavior is an essential component for cooperation to evolve since it allows individuals the proximity necessary to transfer information or resources.
Additionally, MITEs can give rise to short interfering RNA genes and regulate genes that are not necessary in their proximity (Piriyapongsa and Jordan 2007, 2008; Kuang et al. 2009).
The notion that physical proximity is necessary for attachment seemed obvious (if not tautological) since a sufficient degree of interactivity seemed necessary for a child to form a close relationship with another person, and there was no modality for inter-activity other than physical proximity.
Induced proximity is necessary and sufficient for HOTTIP RNA activation of its target genes.
For example, spatial proximity is necessary for enhancers to modulate transcription of target genes (for example, refs 5, 6, 7), and clustering of chromatin near the nuclear lamina is correlated with gene silencing and replication timing8,9.
In order to network with someone, often times a degree of proximity was necessary.
Since Bowlby [1] first introduced attachment theory, it has been accepted that physical proximity is necessary for young children to form and maintain a secure attachment with an adult.
