Jablonka also argues that the requirement for high fidelity of replication (e.g., Sterelny 2001) is not as necessary for inheritance systems that employ filtering mechanisms that ensure that transmitted variations are typically adaptive (Jablonka 2002).
They note that the Hoyle conditions are a product of evolution, not a necessary precondition for inheritance that can support evolvability.
The alternative conformation of chromatin at centromeres may be necessary for centromere inheritance in the case of regional centromeres or more generally for centromere function [ 33], but may also expose centromere DNA to higher rates of mutation and sequence evolution.
Since their parents were mysteriously killed in a fire, the orphans are forced to live with Count Olaf, their cousin/uncle who goes through any means necessary to steal their inheritance.
Reliable inheritance is necessary in order for epigenetic variation to be a major component of any evolutionary process.
Although the possibility that MODY mutations have a causal role in this group is remote, the exclusion of the most common MODY mutations by sequencing the whole HNF1A and GCK genes is necessary given the peculiar inheritance and onset patterns.
The approach of Sun et al. [2002] and our extension of this method do not provide estimates of parameters that describe the underlying genetic model, with the benefit that no assumptions about the mode of inheritance are necessary.
The presence of the euchromatic target transgene is not necessary to establish the maternal inheritance of TSE, responsible for its epigenetic behavior.
Prokaryotes can be expanded to eukaryotic volume via extreme polyploidy [ 23], but cytoplasmic inheritance is strictly necessary for energetic expansion, as it alone enables the loss of the vast majority of endosymbiont genes, while retaining the few genes needed to maintain control over oxidative phosphorylation across a wide membrane area [ 34].
Philip, aged 19, is strangely devoted to his elderly mentors; the novel, Uncle Joe-Joe and The Blackbird, unfolds the necessary and often uneasy consequences of inheritance on a stage both epic and intimate.
