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These results indicate that although PPARs are not necessary for the ability of EPA to induce FGF21, they may contribute to some of the effects of EPA.
The central section of the Gγ subunit was found to be necessary for the ability of a Gγ subunit to mediate signaling involved in PGC migration.
The introduction of the inorganic phase (silica) is necessary for the ability of fast reswelling and also results in a strong improvement of the hydrogels' mechanical properties, while the maximum swelling degree remains nearly unaffected.
Recent in vitro studies have suggested that Akt signaling is necessary for the ability of ActRIIB inhibition to induce muscle hypertrophy.
IL-10 is a potent anti-inflammatory cytokine [65], [66] and Gerber et al. demonstrated that IL-10 was necessary for the ability of type-II activated macrophages to rescue mice from a lethal dose of LPS [7].
Moreover we have shown that BCL2 is necessary for the ability of MYB to protect such cells against DIA-induced apoptosis.
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Although some degree of load sharing is necessary for fusion, the ability of the instrumentation system to transfer the load may vary.
The IGFI receptor (IGF1R) is necessary for the transforming ability of several oncogenes, suggesting that parallel growth factor signaling-mediated metabolic changes are crucial for cellular transformation [ 74].
This is necessary for the state's ability to maintain public order and to assure those who do see it as an authority that it will be able to do what it is supposed to do.
Although lignin is a key polymer providing the strength necessary for the plant's ability to grow upward, a reduction in lignin content down to 64% of the wild-type level in Arabidopsis was tolerated without any obvious growth penalty.
Collectively, these results provide evidence for the C-terminus of HSPB1 being necessary for the protein's ability to protect cells against misfolded proteins either by direct chaperoning function or through the diminished amount of HSPB1 dimer, independent of nuclear translocation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com