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These were an unmodified wild type (WT) gene, one with a mutated 3′ splice site in intron 1 (In1m), one with a mutant poly(A) site (pAm), as well as versions of In1m and pAm lacking the 3′ flanking sequence necessary for termination (ΔTIn1m and ΔTpAm).
Similar(59)
The C terminus might interact with elongation or termination factors, or with other proteins necessary for efficient termination.
Pierrehumbert, R. T. High levels of atmospheric carbon dioxide necessary for the termination of global glaciation.
S9 might interact with one of the elongation or release factors that are necessary for efficient termination and ribosome recycling [ 31- 33].
By chance the 3' UTR of the new neighbor on the opposite strand contained all the signals necessary for transcription termination so that the translocated gene could continue to function.
Indeed, most existing computational models of the EGF activated ERK pathway, including the original Brown model, do not include receptor degradation [ 11, 29, 38] or predict that it is not necessary for signal termination [ 28, 33].
Conversely, Plaintiffs contend that the ordinary course of business exception is narrow and applies only when an electronic communication service provider's actions are "necessary for the routing, termination, or management of the message". See ECF No. 53 at 7. The Court finds that the ordinary course of business exception is narrow.
Furthermore this indicates that relatively less information is necessary for transcription or translation termination.
If the head of the department concerned refuses to take responsibility for such procedures, the Board of Governors shall create a unit equipped with the means necessary for the performance of voluntary termination of pregnancies.
The algorithm reads entire ORFeomes but discards the first and last 3 codons which have specific contexts necessary for efficient translation initiation and termination (e.g. [ 39]).
The intergenic regions contain conserved sequences necessary for the proper initiation and termination of transcription of all open reading frames [ 3– 5].
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