Sentence examples for necessary for activity from inspiring English sources

Instead, we propose that both the interfacial flap and the hydrogen bond network enhance interactions between the two catalytic subunits and guide an optimal conformation of the active center necessary for activity.

On the basis of our structural studies and mutagenesis data, we propose that both the interfacial flap and the hydrogen bond network enhance interactions between the two catalytic subunits and guide an optimal conformation of the active center necessary for activity.

The mechanisms proposed by Hashimoto et al. and Martinez et al. involve mainly α-subunit residues and particularly the cysteine-sulfenate oxygen, known to be necessary for activity, to act as a general base in activating a water molecule to attack the metal bound nitrile or as the nucleophile itself, respectively.

The data reveal that though metallic Rh nano-particles are the base for an active catalyst, a surface oxide species (RhO) is likely necessary for activity.

Together, these data further highlight the importance of PHD1 in KDM5 enzymes, and parallel in vivo observations that this domain is necessary for activity of KDM5B44,68 and its drosophila homolog Lid56.

As a further test of this conclusion, the paclitaxel analog 4 was designed as a compound which has all the chemical functionality necessary for activity, but which cannot adopt the T-Taxol conformation.

These findings suggest that the 5-HT1A receplaysplans an inhibitory role in behavioral phase shifts, a facilitatory role in light-induced gene expression, a necessary role in phase shifts to 8-OH-DPAT, and is not necessary for activity-induced phase advances that oppose photic phase shifts to long light pulses.

Hand function is necessary for activities of daily life.

Such registrations are necessary for activities that involve influencing policy and public opinion in the United States, and some of Mr. Manafort's Ukraine work appeared to fall into that category.

No such elaborate descriptions are necessary for activities or achievements.

Synaptic vesicle exocytosis may provide the pathway necessary for activity-dependent delivery of AMPA receptor subunits to the surface [40].