Sentence examples for necessary efficacy from inspiring English sources

Thus, creation of multi-component vaccines is unlikely to be justifiable until it is known that careful optimization of formulation results in a vaccine that just fails to achieve the necessary efficacy or the proportion protected.

It is still unclear whether high levels of cytokine production may be necessary for efficacy of an rCTL agent and what the clinically tolerable level of cytokine release might be (Lum and Thakur, 2011).

This standard is tarnished by the expense and the long period sometimes necessary for efficacy to be evident (1 3 months in most studies).

Behavioral effects in the TST are often seen after acute treatment with SSRIs, even though chronic treatment is often necessary for efficacy in human patients.

In fact, the published experience with epratuzumab in lymphoma, in which cell killing is presumably necessary for efficacy, suggests that this agent has only very modest capabilities when used alone and unaltered.

Interestingly, the HuCNS-SC-mediated impact on cognition and synaptic and growth associated markers occur within a relatively short time post-transplantation (4 6 weeks), when most donor cells are still relatively immature, suggesting that a specific differentiation program may not be necessary for efficacy; rather, intrinsic properties of HuCNS-SC may be more relevant in these models.

The model assumes that an individual must be well-informed, motivated, and possess the necessary self-efficacy behavioral skills to initiate preventive behavior [ 21].

Further study is necessary to examine efficacy.

Adjustments are necessary to improve efficacy and avoid instability, modifying existing feedback control loops.

Studies reviewed were inconsistent in methodology and design necessary to establish efficacy or association.

Before entering the clinic, however, in vivo studies in immunocompetent animals are necessary to prove efficacy and provide information on safety aspects.