From our study, we determined that both the intensity of the IHC staining of pAkt and the percentage of tumor cells stained with pAkt were necessary determinants for the scoring system.
The polyvalent vaccines, such as autologous whole-cell vaccines represented by PDT vaccines, secure greater coverage of potential/diverse tumour antigens (even if most of them are unknown) and include the necessary determinants for helper T cells (Copier and Dalgleish, 2006; Emens, 2006).
Together, these data show that mesenchymal FGFR signaling is a necessary determinant of cochlear length and sensory progenitor proliferation, but not for cochlear pattern formation or differentiation.
We have reworded the paragraph to state that mesenchymal FGFR signaling is a necessary determinant of cochlear length and sensory progenitor proliferation, but not for cochlear pattern formation or differentiation.
Our data underline the importance of HPA axis dysregulation for treatment outcome in major depression, although restoration of HPA system dysfunction seems to be neither a necessary nor a sufficient determinant for acute treatment response.
Skills is also used as a determinant based on de Vries' [ 49] contention that this is a related factor to behaviour change and the assertion by Kok et al. [ 46] that having the necessary skills to perform the behaviour is among the necessary and sufficient determinants for behaviour change.
This inability to predict SoxS binding sites suggests that addition of sequence determinants is necessary for determining SoxS-mediated expression.
Analyses of the localization pattern of mutant RomR proteins consisting of one of the two domains suggested that the output domain is a pole-targeting determinant for RomR and contains the information necessary and sufficient for bipolar, asymmetric localization.
Thus, while stem cells represent an important determinant for tissue regeneration, a "qualified" environment is necessary to guarantee and achieve functional results.
Therefore, the presequence seemed to be the determinant for mitochondrial targeting, and the question arose whether the Par17 N-terminus was necessary and/or sufficient for mitochondrial targeting.
