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That, in the end, provides a neat feedback loop.
Mechanistically, the observation of potent combination effects is difficult to fit into a simple model in which VEGF signalling induces Dll4-Notch activity in the vasculature, which subsequently helps to downregulate VEGF pathway activity in a neat feedback loop.
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What's neat about this service is the statistical breakdown and the ability to tailor the feedback system.
Neat trick.
Neat piece.
Neat, huh? Neat, huh?
Very neat.
Neat, eh?
Neat stuff.
Neat worksheets?
Grant: Neat.
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