Overexpression of ARO10 in strain Isoy21 could nearly fully substitute the KDC activity of Pdc enzymes (32.83 ± 8.72 mU mg protein-1) whereas kivD overexpression resulted in only partial complementation (19.61 ± 2.52 mU mg protein-1).
In place of that unlimited coverage, which had become nearly universal, insurers substituted a similar-sounding policy with a crucial difference: it pays only the amount stated on the policy plus, typically, an additional 20percentto25percentcent.
Now fans can judge for themselves: in the Euro 2008 final, Spain's Cesc Fabregas ran nearly 8km (nearly five miles) before being substituted in the 63rd minute.
Since the punishments of whipping and of standing in the pillory were abolished by the act of February 28 , 1839 c. 36, § 5, (5 St. 322,) imprisonment at hard labor has been substituted for nearly all other ignominious punishnents, not capital.
"Yes, many may find another method," said Catherine Barber, director of the Harvard center's Means Matter public health education campaign, "but will it kill them?" Citing statistics from emergency rooms and death certificates, she said, "Nearly everything they substitute will have lower odds of killing them, sometimes dramatically so".
Thus the introduction of the system in question in the Northwest made it possible to substitute nearly all non-selected carp stocks in the industrial fish farms by selected broodstock.
In a quick bread, such as a muffin or biscuit, you can substitute nearly all of the flour for quinoa, noting that the bread will be more brittle and crumbly as more quinoa is added.
The adjusted relative risks for the hospitals were nearly identical in models that substituted the chronic disease score, which incorporates preoperative prescription drug information along with age and sex, in place of age and sex as separate risk factors.
Twenty-two percent said that they never accepted substitution, of whom nearly half had had their drugs substituted anyway without being aware of it.
The InChIKey is designed to be a nearly unique substitute for the parent InChI.
