Second, the side buttons that you are supposed to squeeze to activate are almost non-functional.
Nearly one in every three schools in Greater Upper Nile is non-functional and 413,000 children have been forced out of school.8 Building on lessons learned, UNICEF will deploy Rapid Response Mechanism (RRM) teams to access vulnerable populations in most-affected areas.
Most of the medical equipment is non-functional.
Nearly one third of the intI genes that we uncovered are predicted to be non-functional, containing either a stop codon, a frameshift mutation, or a major insertion or deletion that would likely render them inactive (*, Additional File 1).
If repetitive DNA elements could be equated with non-functional DNA, then one would surmise that the human genome contains vast non-functional regions because nearly 50% of nucleotides in the human genome are readily recognizable as repeat elements, often of high degeneracy.
They represent molecular prostheses for non-functional cellular activity; they differ from other synthetic networks that add useful functionality but do not replace non-functional cellular networks.
Variants designated as non-functional in Findlay and colleagues' analysis generally corresponded with those annotated as deleterious in the database, and, reassuringly, nearly all functional variants corresponded with those annotated as benign.
As the number of fragment continues to increase beyond 50 million, nearly all new positions detected were within antisense regions of the genome, many of which, as discussed above, may correspond to non-functional spurious transcripts or gDNA contamination.
The sequence homology between functional mouse and non-functional human FSs is shown in Figure 3.
Non-functional paralogues that often lack promoter or intron sequences.
Non-functional, non-intuitive, and/or missing equipment.
