When co-transfected with miR-137 or miR-544 in HEK293 cells (which do not naturally express these two miRNAs), the expression of the miRNA-specific reporter pFL-BRCA1 was significantly suppressed compared to pFL-BRCA1-mut, confirming the role of miRNA-mediated surveillance in repressing its target.
Choorapoikayil et al. studied the consequences of reduced PTEN expression using mutant zebrafish (which naturally express two functional Pten genes).
Moreover, expression from the JAG1 3′UTR reporter was lower in PNT1A cells, which naturally express the endogenous mir-200c∼141 cluster, compared with the expression from the mutant sensor construct (Supplementary Figure S3B).
Similarly, digital media naturally express choice.
She looks too sweet for anything but sweet parts; and although her voice is musical, it doesn't naturally express hard emotion.
Our current Vietnam vocabulary seems to aspire to a destruction not only of the meaning but also of the feeling that language should should naturally express.
McGonigal's program aims to build on the "connection between the strengths you naturally express when you play games and the strengths you need to be happy, healthy, and successful in real life".
Participants then viewed a sadness- or humor-eliciting prime under instructions to inhibit or naturally express emotion.
Moreover, the proposed multi-model strategy can also naturally express the relative certainty of different hypotheses, by adhering to each with their prescribed frequency.
If you have no doubt of your premises or your power and want a certain result with all your heart you naturally express your wishes in law and sweep away all opposition….
Some theorists would claim that (21) is true only if John has a first-person desire, that is, a desire that he would naturally express with 'I want to eat a large slice of pizza'.
