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Unfortunately, since ComK is a transcriptional regulator with pleiotropic effects, its overexpression will disturb natural gene expression patterns.
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Selection of pathways (concepts) based on the statistical significant enrichment score (ES) is one natural way to infer function from gene expression patterns.
Our analyses of natural selection and the evolution of gene expression patterns were then considered in light of this broader phylogenetic context to draw conclusions about the model of evolution and possible gene fates of NP-like genes and proteins within Populus.
The concept of EDGE is based on the hypothesis testing of differential gene expression patterns fitted by natural cubic spline interpolation.
To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between experimental and natural disease.
Metatranscriptomics is rapidly expanding our knowledge of gene expression patterns and pathway dynamics in natural microbial communities.
These findings cannot reflect the full range of gene expression patterns that occur in the natural environment, where multiple factors (e.g. sunlight, water, nutrients) may vary at the same time.
In natural populations of non-model organisms, two approaches can be used to determine the "normal" gene expression patterns (Neumann and Galvez 2002).
For example, natural [ 23, 24] and synthetic [ 25, 26] regulatory circuits can produce unique gene expression patterns in response to distinct combinations of signals endogenous to a cell.
Comparison of gene expression patterns using locust microarrays is an alternate approach to understand the natural selection and adaptive evolution of TP locusts [ 15, 16].
The mortality and gene expression patterns could have been influenced by the proximity to final maturation and processes associated with natural senescence.
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