Sentence examples for native reactions from inspiring English sources

In keeping with the in vivo results, the catalytic efficiency of the native reactions is reduced by at least 95-fold, and α,β versus α,γ-elimination specificity is not modified.

Thus methyl substitution by itself (as revealed by topoisomerase) or this substitution plus the removal of a catalytic arginine residue (as revealed by Flp(R308A) can dramatically alter the native reactions qualitatively.

Many enzymes exhibit the ability to catalyze, at a low level, the native reactions of related enzymes.

The flux of native candidate reaction was set to be zero and the flux of the added reaction was set to be M-fold of the initial flux of native reaction (M = 0.1, 0.2, 0.3… and 2.0).

The native reaction channel produces Tryprostatin B, while the Gly115Thr mutant produces a product not seen in the native enzyme (see Figure 1).

We find the barrier for abstraction of the H8 atom to be kinetically noncompetitive to the native reaction (4.0 ± 0.5 kcal mol 1 higher than the native hydrogen abstraction reaction, see Supplementary Figure 4, Supporting Information).

Precisely, the method of Pharkya et al. [ 9], is aimed at redesigning microbial chassis organisms through heterologous reaction addition and native reaction deletion for the overproduction of a target compound.

The mathematical representation of metabolic networks enables analysis of the metabolism using optimization methods to identify internal flux distribution, metabolic capabilities, and strain improvement strategies through gene knock-out or insertion of non-native reactions [ 17, 24- 26].

To answer these questions, a systematic computational assessment of Escherichia coli's potential ability to produce different chemicals was performed using an integrated metabolic model that included native E.coli reactions and known heterologous reactions.

Interestingly, this employment reaction is of similar magnitude to that reported in Borjas (2003) and Aydemir and Borjas (2007) when focusing on native wage reaction.

The first is achieved by elevating the expression of transketolase I (TktA) and the second by blocking the native oxidation decarboxylation reaction of E. coli by deleting the zwf gene from the chromosome (designated as JB/pTA and MZB, respectively).