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The native mechanisms of tolerance, notably those of active suppression by regulatory cells, have therefore fascinated immunologists from the beginning on as they promise modulation of the immune system in an antigen-specific way.
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It should be noted that the powders obtained by sol-gel method formation of apatite are similar with the formation of apatite in bone native mechanism: colloidal solution-amorphous condensate-crystal phase.
At this time it is difficult to discriminate if the former is due to strong interaction with the substrate or if it really corresponds to native mechanism.
By regulating multiple targets, including the key NSC factor Notch 1, a miR-146a-mediated innate regulatory mechanism provides a native safeguarding mechanism to restrict the formation of glioma stem-like cells and glioma growth by directly controlling expression of Notch 1 [ 24].
Native reparative mechanisms exist but are inadequate to vascularize ischemic myocardium.
Under chemical stress, native adaptation mechanisms combat hyper-fluidization by modifying the phospholipids in the membrane.
This possibly devastating condition, particularly in high-level athletes, is also linked to the impairment of native repair mechanisms to defend the tendon from degeneration and ultimately rupture.
Exploiting the signaling pathways activated by biomaterials can provide insight into native signaling mechanisms crucial for tooth development and cell-based strategies for enamel regeneration.
This has proven infeasible to date due to the lack of native measurement mechanisms that can form an integral part of the network's main forwarding operation.
For the production of these heterologous proteins, native secretion mechanisms are most frequently used [ 73].
The primary design of the Vibrant Soundbridge marries a floating mass transducer to the incus to deliver mechanical energy through the native conductive mechanism.
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