Exact(5)
As a background, we first assess the mtDNA diversity of the two species in their native basins from comparable datasets.
A strong regional substructure has evolved since that time, in contrast to the apparent broad-scale uniformity maintained by herrings in their native basins.
A strong regional substructure has evolved since that time in Europe, in stark contrast to the broad-scale uniformity maintained by herrings in their native basins.
We further assess the structure of the "invading" C. pallasii among and within the NE European seas, and document striking regional differences that contrast with the homogeneity of the herring stocks in their native basins.
The Atlantic and Pacific herrings both feature high mtDNA diversities (large long-term population sizes) in their native basins, but an ocean-wide homogeneity of C. harengus is contrasted by deep east-west Pacific subdivision within Pacific C. pallasii.
Similar(55)
Furthermore, the native basin exhibits a hierarchical organization, which is not found for a random heteropolymer lacking a predominant free-energy minimum.
The obtained results, including the population of the native basin, the free-energy landscape as a function of the number of native contacts, and the folding kinetics, also suggest that the hbSBD domain is a two-state folder.
MRR simulations of the Met-enkephalin pentapeptide, and the 76-residue protein ubiquitin, performed in presence of explicit water molecules and totaling 32 ns each, investigate the ability of MRR to characterize the conformational landscape of the peptide, and the protein native basin, respectively.
For example, it is of interest to select θ to be one of the following: θ nat, θ TS, or θ unf, which identifies the native basin, the assumed transition state maximum, and the unfolded minimum, respectively, in the function G θ,T m ).
The origin of this difficulty lies in the fact that the potential energy function used for the simulation may not be as accurate as it should be, so that the lowest-free-energy basin may not correspond to the true native basin.
The PMF was characterized with an energy barrier of 3 kBT located at 2.7 nm from the native state basin.
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