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There were no signs of degeneration detectable and continuous native-analogous growth was confirmed by vessel-volumetry.
We will refer to such a 'default' phenotype as G's native phenotype (analogous to the native conformation of a protein).
In this work, we elucidate the role of lipid modification through a series of all-atom molecular dynamics simulations on siRNA complexation mediated by a native PEI and four analogous obtained by different lipid modifications.
Seleno-L-Met-substituted protein was expressed as described [33] and purified analogous to native protein with the addition of 1 5 mM DTT in all buffers.
GLP-1 receptor agonists analogous to native GLP-1 have thus been developed as an alternative approach to increase GLP-1R activity in the treatment of type 2 diabetes.
Furthermore, tuning the local hydrophobicity of the resin particles with an approach analogous to the native enzyme hydrophobic pocket increased the catalytic efficiency.
The physical-chemical features of the scaffolds characterized by XRD, FTIR, ICP and TGA demonstrated structural mimicry analogous to the native bone.
We also performed experiments to rescue the inviable yeast mtHsp70 (Ssc1 -null Ssc1 -nullh either native strainr Ssc1 carrying the analogous PD-associated variants (R103withc1 ≙ human R126W mortalin; P486S Ssc1 ≙ human P509S mortalin).
Ideally, biomaterials designed to play specific physical and physiological roles in vivo should comprise components and microarchitectures analogous to those of the native tissues they intend to replace.
Design of biomaterials for cell-based therapies requires presentation of specific physical and chemical cues to cells, analogous to cues provided by native extracellular matrices (ECM).
These membrane-associated dimer S-MB peptides may possibly self-associate to form protein-rich networks in lipids, analogous to those observed for native SP-B and other SP-B peptides containing the insertion sequence [32], [116].
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