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Varicella-zoster virus is the causal agent of varicella (chickenpox) currently the most widespread preventable childhood disease in industrialised nations where many other infections are well-controlled by national vaccination programmes [ 1, 2].
Such gaps in immunisation have important implications for effective national vaccination programmes.
Finally, there are continuing, but as yet unheeded, calls for national vaccination programmes in endemic areas [see 13], [74], and where single TBE cases are being increasingly reported from so-called low risk areas [71].
Undertaking a randomised controlled trial to assess VE is now impractical due to the presence of national vaccination programmes.
International organisations and donors have chosen to use DTP3 coverage as the main indication of the effectiveness of national vaccination programmes.
With the control of many infections through national vaccination programmes, varicella is currently the most widespread preventable childhood disease in industrialized nations.
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The decision to include a vaccine in a national vaccination programme (or not) is usually evidence-based.
10 The target population consisted of at least 9000 participants vaccinated according to the national vaccination programme at participating general practices.
The Mexican Public Health Institutions provided trivalent inactivated influenza vaccine as part of the national vaccination programme.
Regardless, our findings support local vaccine promotion strategies within a national vaccination programme.
The study was done in the Netherlands when whole-cell pertussis vaccine was used in the national vaccination programme.
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