Your English writing platform
Discover LudwigSuggestions(1)
Exact(7)
Arrowheads indicate nascent lipoprotein particles.
Arrowheads indicate nascent lipoprotein particles in smooth ER lumen.
These newly synthesized lipids are incorporated into nascent lipoprotein particles.
ApoB-100 is associated with hepatic-derived non-HDL-C and is incorporated into nascent lipoprotein particles, along with cholesterol and triglycerides [ 47].
10.7554/eLife.06557.019 Figure 9. Reduced nascent lipoprotein particle size in the lumen of Golgi and secretory vesicles in Lpcat3-deficient liver.
Second, we have added new EM data that directly assess the size of nascent lipoprotein particle in the ER and Golgi.
Similar(53)
MTP is an intracellular protein located in the endoplasmatic reticulum, which transfers neutral lipids onto the apoB polypeptide and participates in the subsequent lipidation of the nascent lipoproteins [27].
MTP also transfers TGs to generate apoB-free lipid droplets in the ER lumen (Kulinski et al., 2002), which are required for TG enrichment in nascent lipoproteins.
Nascent lipoproteins, ranging between 0.05 and 0.11 microns in diameter, were easily visualized in the Golgi apparatus and secretory vesicles of control mice.
MTP is located in the lumen of the endoplasmic reticulum (ER) and is involved in the initial loading of nascent lipoproteins with neutral lipids, particularly triglycerides and cholesterol esters.
This change in membrane composition creates a dynamic membrane environment that facilitates the transfer of TG synthesized on ER and/or in cytosolic LD to nascent apoB containing lipoproteins particles, leading to the efficient lipidation of apoB containing lipoproteins.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com