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If possible, larger studies should be conducted to provide narrower estimates of this failure rate.
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In some circumstances the combined uncertainty, particularly over the long term, makes it difficult to determine the balance of costs, co-benefits, and co-harms, but additional methods can help narrow estimates substantially, particularly in the near term.
15 Meta-analyses of small trials can provide evidence of benefit with what seem to be narrow estimates of precision; however, such reviews have often been subsequently refuted by large trials.
In December, app analytics company Distimo claimed that the revenue gap between Apple's App Store and Android's Google Play store was narrowing, estimating that on a typical day in November, global revenues for the 200 top grossing iOS apps were more than $18m versus $12m for the comparable selection on Google Play – compared to $15m and $3.5m respectively a year before.
The numbering (1, 2, and 3) corresponds to the configurations shown in Figure 3 figure supplement 2. This analysis provides the narrowest estimate for the range of N w for each data point Δ x (colored bands).
Coronary artery disease was defined based on angiographic criteria as the occurrence of at least one stenosis of at least 50% in at least one of 15 coronary segments, using the maximal luminal narrowing estimated by standardized visual analysis.
The severity of coronary artery disease is stated in the Research Design and Methods section (2): "Coronary artery disease was defined based on angiographic criteria as the occurrence of at least one stenosis of at least 50% in at least one of 15 coronary segments, using the maximal luminal narrowing estimated by standardized visual analysis".
Priceline said that its first-quarter loss was narrower than estimates had been and that it expected to turn a small profit in the current quarter, helped by steep cost reductions and a heightened focus on its core travel business.
At least seven analysts had narrowed their estimates in the last 30 days after the company said May orders of plastics and appliances missed expectations.
More focused stratification for advanced liver fibrosis (0·9 2·0%) or cirrhosis (0·1 1·7%) narrowed the estimates of prevalence.
There were several traits for which we found no significant dominance component, resulting in equal broad and narrow heritability estimates.
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