Sentence examples for narrow specificity from inspiring English sources
In the recent study of serum biomarker, Jung et al. took the advantage of narrow specificity lectins, which target more specific features of glycosylated-proteins to study disease associated aberrations in glycosylation [ 24].
Thus, FAP is a narrow specificity endopeptidase and this can be exploited for inhibitor design.
Channels may possess a narrow specificity, allowing passage of only potassium or sodium, or a broad specificity, allowing passage of all positively charged ions (cations) or of all negatively charged ions (anions).
The sandwich ELISA using rabbit anti-β for the capture antibody and horseradish peroxidase-labeled F ab′ 2 fragment of rat anti-β for the detection antibody obtained high sensitivity and narrow specificity for SYP.
This family containing the α/β hydrolase fold has a distinctive substrate profile that allows it to carry out hydrolysis of esters containing diverse alcohol moieties while maintaining narrow specificity for an acetate ester.
With a reciprocally designed initial and second-exposure protocol (i.e., all combinations of bacteria were tested), we demonstrate, even several weeks after the clearance of a first exposure, increased protection and narrow specificity upon secondary exposure.
CotA is a generalist, an enzyme with broad specificity, and it was optimized to be a specialist, an enzyme with narrowed specificity.
Our results suggest that the design of immunogens for anti-V3 antibodies should avoid the Arg at the V3 crown, as GPGR-containing epitopes appear to select for B cells making antibodies of narrower specificity than V3 that carry Gln at this position.
a The origin of enzymes with narrowed specificity from an ancestral unspecific one.
These structural data have guided the discovery of inhibitors with narrowed specificity toward FGFR kinases.
The most parsimonious evolutionary conclusion would be that in the low-GC gram-positive grouping, acquisition of the ACT domain and narrowed specificity for prephenate preceded narrowed specificity for NAD+.
