Sentence examples for naive lymphocytes from inspiring English sources

Significant differences were also observed between previously activated memory lymphocytes and naive lymphocytes, indicating a relationship between cell-cycle potential and nanoparticle susceptibility.

Lymph nodes are compartmentalized structures organized to facilitate entry and migration of naive lymphocytes to areas of antigen presentation, activation, and expansion.

The primary lymphoid tissues are the place where lymphocyte precursors develop into immunocompetent naive lymphocytes.

Naive lymphocytes, when stimulated by an antigen, develop into memory lymphocytes, which subsequently differentiate into effector lymphocytes.

In contrast, DCs are able to initiate and modulate adaptive immune responses through recognition and phagocytosis of pathogens at the sites of infection, and through subsequent cytokine secretion and migration to the draining lymph nodes where they process and present antigens to naive lymphocytes.

A detailed study comparing naive lymphocytes and lymphoblasts provided evidence that several didemnins exhibited a cytotoxic, but also a targeted mode-of-action [28].

S1PR1 is thought to regulate naive lymphocyte egress from the lymph node via the lymphatic vessels by sealing the lymphatic endothelial barrier and disallowing naive T cell egress from lymph node and thymus (Alfonso, McHeyzer-Williams, & Rosen, 2006; Sanna et al., 2006).

While we haven't investigated the member(s) of the S1P receptors family known to be affected by FTY720, we can only speculate that S1P1, the master player controlling naive lymphocyte egress from the LNs is not expressed on memory CD8+T cells that do not home to LNs.

Over the years these studies evoked a large controversy on the production rates, division rates, and lifespans of mouse and human lymphocyte populations, leaving fundamental questions such as the maintenance of memory, the maintenance of a diverse naive lymphocyte repertoire, and the nature of homeostatic mechanisms largely unresolved [ 43].

In brief, antigen-acquiring dendritic cells (DCs) pass from the site of the primary tumour to the regional LN, wherein they present antigens to naive T lymphocytes, converting them into specifically sensitised T lymphocytes such as helper T lymphocytes or cytotoxic T lymphocytes.

Dendritic cells (DC), which are potent antigen presenting cells capable of priming naive T lymphocytes and subsequently inducing cytotoxic T lymphocytes (CTL) by stimulation of Th1 type immune response, play a central role in cell-mediated immunity (Janeway et al, 1997; Banchereau and Steinman, 1998).