Sentence examples for na development from inspiring English sources

We further explore the utility of this Xenopus system for characterising normal NA development and differentiation of NA cells within the signalling context of NB, by experimental manipulation of cyclin-dependent kinase (CDK) and N-Myc levels on NA cell differentiation, mimicking similar perturbations found in NB.

This failure to differentiate is potentially the result of improper extracellular signalling in the anteroventral region; for example, BMP2 signals, which are required for normal NA development in mammals (Howard, 2005) and for AVNA cells in Xenopus (Parlier et al., 2008) are not received.

We compared gene expression in NB to ascertain whether this resembled an expression profile similar to a particular stage of normal NA neuron development.

Influenza NA inhibitor development is regarded as a classical example of structure-based drug design and the continued structural analysis of influenza NAs has contributed greatly to the design and evaluation of effective anti-influenza agents.

This suggests that NB is either stalled at a stage in development after NA markers have been expressed, but prior to ASCL1 downregulation, or that ASCL1 is aberrantly actively maintained at a high level.

Data from different studies suggest that both MeCP2 overexpression and MeCP2 loss of function result in complex phenotypes in dendritic development (Na et al., 2013; Zhou et al., 2006; Jiang et al., 2013; Cheng et al., 2014).

It has indeed been shown that the glycogenolytic response of astrocytes to NA changes throughout development [ 28].

This led us to consider what influences the cell cycle might have on differentiation of both sympathetic NA cells during development and on NB cells under pathological conditions, as well as potential mechanisms for such an influence.

The following clinicopathological data were retrospectively reviewed: gender, age, presence of liver cirrhosis, HBeAg status, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alpha-fetoprotein (AFP), the duration of LAM use before inclusion, subsequent use of ADV or ETV, total duration of NA use, and development of HCC or liver failure.

Currently, NA-based drug development against resistant influenza A virus aims to search for novel compounds effective to treat predominant H274 mutant strains.

PAI was first observed in Na [49] with the development of the MOT technique.