(2, 3, 8) To date, many preclinical studies have hinted at the myriad of pathways that can be targeted for a synergistic and multitargeted approach.
During the past few years, although progress has unraveled a myriad of pathways that can induce mitotic catastrophe, it is still poorly understood [ 30, 35].
A clearer picture is beginning to emerge out of the myriad signaling pathways that have been implicated in disease-related pain hypersensitivity.
Ligand receptor interactions govern myriad cell signaling pathways that regulate homeostasis and ensure that cells respond properly to stimuli.
To compare the functional roles of REST and CoREST, we analyzed profiles of REST and CoREST target genes in neuronal subtypes using Ingenuity Pathway Analysis and found a myriad of enriched pathways that may play roles in neuronal subtype elaboration (Table 1).
Fundamentally, organisms utilize a myriad of signaling pathways that drive physiological adaptation to diverse environmental stresses, including temperature fluctuations and osmotic, oxidative, and weak acid stresses, as well as nutrient limitation (6, 7).
Since then, investigators including Ruslan Medzhitov have mapped out a myriad of different receptors and pathways that are involved in the mechanisms of pattern recognition.
There are many potential ligands for this particular receptor, and although he'd blocked them all in the mice, he couldn't do that in a person without potentially interfering with vital signaling pathways that could produce myriad serious side effects.
Autism exhibits phenotypic heterogeneity, which suggests that a mechanistic route does not encompass a single pathway but includes disturbances to myriad pathways or processes that culminate in an autism diagnosis (Fig. 1).
