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We review the latest advances in our understanding of the mechanisms underpinning endosomal transport and positioning, with emphasis on the contributions from the ER, and offer a perspective on how the interplay between these aspects shapes the architecture and dynamics of the endosomal system and drives its myriad cellular functions.
Gene ontology (GO) enrichment analysis using the DAVID functional annotation tool [ 29] identified enrichment of genes involved in myriad cellular functions following activation of MYC.
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These genes have varying degrees of sequence similarity to each other and are involved in a myriad of cellular functions [ 15].
Microtubules (MTs) are the fundamental structural elements of all cells that govern a myriad of cellular functions, including motility, maintenance of cell morphology, intracellular transport, mitosis and meiosis.
HDACi are a novel class of structurally diverse natural and synthetic compounds that modulate a myriad of cellular functions by inhibiting HDAC activity.
In the present review, we focus on cytoplasmic dynein, which is required for a myriad of cellular functions in interphase, mitosis and meiosis, ranging from transport of organelles and functioning of the mitotic spindle to chromosome movements in meiotic prophase.
As the PI3K/AKT/mTOR axis is such a crucial signalling axis in mediating a myriad of cellular functions essential in both normal development and during carcinogenesis, many research groups have focussed on elucidating the convoluted regulation of these pathways.
These genes encode proteins that function either as growth factors, as inducers of angiogenesis or as extra-cellular matrix signalling proteins that facilitate the process of new vessel development or regulate a myriad of cellular functions, such as cell adhesion, proliferation and migration, which are essential for tumour angiogenesis and metastasis.
We contend that not only may the forecast increases in solar radiation in both aquatic and terrestrial environments significantly affect members of the Apicomplexa, solar UV-induced membrane depolarizations resulting in cytosolic calcium perturbation may affect a wider range of eukaryotic organisms through antagonistic effects on a myriad of calcium dependant cellular functions.
Considering the myriad cellular processes that keep our body functioning, a clear and reinforcing realization is that many genes encode more than one protein, a theory replacing the old notion of one gene one protein.
In this study, we found that CCT- β interacts with a myriad of intracellular proteins involved in the cellular functions of the endoplasmic reticulum (ER), mitochondria, cytoskeleton, proteasome and apoptosome.
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