Sentence examples for myeloma and breast from inspiring English sources
Incidence of osteonecrosis of the jaw in patients with multiple myeloma and breast or prostate cancer on intravenous bisphosphonate therapy.
Cancer patients, mostly those with multiple myeloma and breast cancer whose disease has spread to their bones, generally take one of two bisphosphonates, Zometa or the older Aredia, intravenously.
Ubiquitin-activating enzyme (E1), which catalyzes the activation of ubiquitin in the initial step of the ubiquitination cascade, is a potential therapeutic target in multiple myeloma and breast cancer treatment.
Heparanase accelerates MMP-9 mediated shedding of syndecan-1 in both myeloma and breast cancer [ 17].
Elevated levels of DKK-1 promote bone lesions in multiple myeloma and breast cancer by inhibiting osteoblast activity [ 4– 6].
The latter result, however, is not consistent with the clinical data that pamidronate reduced skeletal complications in patients with multiple myeloma and breast cancer [ 31- 33].
However in osteolytic models of multiple myeloma [10] and breast cancer [8], significant reduction in establishment of bone metastatic lesions was observed, but this is not true for our system (Figure 3).
An additive growth-inhibitory effect of retinoids and vitamin D analogues has been demonstrated for human myeloma, leukaemic and breast cancer cells.
Both solid and hematologic malignancies have been associated with this syndrome; the most frequent etiologies being multiple myeloma, lung and breast cancer [ 3].
It selectively reduced the viability of CSCs in acute myelogenous leukemia (AML), multiple myeloma (MM), and breast tumors., PN decreased the viability of prostate tumor-initiating cells isolated from cell lines and from patients, and inhibited prostate cancer stem-cell-mediated tumor initiation and progression in mouse xenografts.
Methods currently used to analyse osteolytic lesions caused by malignancies such as multiple myeloma and metastatic breast cancer vary from basic 2-D X-ray analysis to 2-D images of micro-CT datasets analysed with non-specialised image software such as ImageJ.
