The remaining 122 papers can be broken down as follows (not mutually exclusive): one-stage 27 papers; two-stage 41 papers; multi-stage/group sequential 23 papers; continuous monitoring 12 papers; decision theoretic 8 papers; three-outcome 4 papers; response adaptive randomisation 10 papers; phase II/III 17 papers; and randomised discontinuation 1 paper.
Unfortunately, products and platforms are mutually exclusive at early-stage startups.
Its simple life cycle and the mutually exclusive growth and development stages make Dictyostelium a popular experimental model to study cellular processes such as chemotaxis, phagocytosis, intra- and inter-cellular communication, cell-cell and cell-substrate adhesion and cellular differentiation.
HLH-1 and PHA-4 target genes would not be expected to overlap in embryos as these two transcription factors are expressed in mutually exclusive tissues at this stage of development.
Both hypotheses are not mutually exclusive but at this stage cannot be disentangled.
It has been observed that although RAS and FGFR3 mutation are mutually exclusive, the grade and stage distribution of these events is different, FGFR3 mutations being most common in low-grade Ta tumours and RAS mutations being distributed evenly across tumours of all grades and stages.
These dynamic patterns of tsh and tio expression are in line with previous observations, where mutually exclusive patterns at early embryonic stages give way to co-expression at later stages (Laugier et al., 2005).
Of course, these initiation pathways are not mutually exclusive, and, at advanced disease stages, persistent injury and persistent inflammation are too closely linked to distinguish cause and consequence.
Taking this into account, earlier results and our own data might not be mutually exclusive, but rather represent different stages in the malignant transformation process with DNA hypermethylation not being an initial but instead a late event for HBV-induced gene repression (for example, CDKN2A).
In wild type, these two gene expression patterns are mutually exclusive for virtually the entire blastoderm stage (Fig. 6).
