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The mutually exclusive localization of αVβ3 and VE-cadherin at cellular junctions in confluent HUVEC suggests that a causal link between cilengitide-induced αVβ3 and Src activation and the disappearance of VE-cadherin from cell-cell contacts.
Note the mutually exclusive localization with the CSD marker CASP1-GFP (green).
Magnified views showed mutually exclusive localization rather than colocalization of RAD21L and REC8 along the axial elements during pachytene in spermatocytes and oocytes (Fig 3B,C).
Remarkably, RAD21L and REC8 have symmetrical, mutually exclusive localization on the not-yet-synapsed homologues, implying that the cohesin patterning could provide a code for homologue recognition.
Thus, the mutually exclusive localization of MglA and MglB sets up a stable polarity axis, which can be dynamically inverted in response to Frz activity.
RAD21L and REC8 have symmetrical, mutually exclusive localization on the not-yet-synapsed homologues, implying that cohesins could establish a code for homologue recognition.
Similar(53)
The two transcription factors exhibit mutually exclusive patterns of nuclear localization in β-cell; constitutive nuclear expression of a mutant Foxo1 is associated with the lack of Pdx-1 expression [26], [27].
Regulatory subunits are mutually exclusive and determine subcellular localization and substrate specificity of PP2A.
Their localizations are mutually exclusive which may provide a general mechanism to establish cortical domains in polar cells.
However, cytosolic and mitochondrial compartimentalizations are not mutually exclusive since evidences for the simultaneous localization of plant and yeast aconitase proteins in cytosol and mitochondria have been reported [ 42].
Alternatively, but not mutually exclusive, cell type specificity may also dictate mitochondrial localization of distinct PTK and the downstream effector proteins within mitochondria.
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