Sentence examples for mutually exclusive interactions from inspiring English sources

Based upon mutually exclusive interactions of FGF2 with PI 4,5 P2 versus heparan sulfates, an assembly/disassembly pathway has been proposed to be the underlying principle of directional transport of FGF2 across the plasma membrane.

Those clustered overlaps are likely to entail different regulatory mechanisms for the spatial or temporal isolation of the mutually exclusive interactions.

This binding was initially proposed to divert Beclin 1 from interacting with and stimulating class III phosphatidylinositol-3-kinase Vps34 activity [19], but a consensus now argues against a mutually exclusive interactions of Beclin 1 with Bcl-2 and Vps34 [24]–[26], underlining that autophagic activity is not solely driven by Beclin 1 association with Bcl-2/Bcl-xL.

At odds with this scheme, under nutrient rich conditions Zeng et al. never detected any Bcl-2/Beclin 1 or Bcl-xL/Beclin 1 interactions [27], and other studies showed that Beclin 1/hVPS34 and Bcl-2/Beclin 1 are non mutually exclusive interactions [24] [26].

Ultimately there may also be clinical applications of mutually exclusive interactions of CIS loci.

Analogously, we performed the same analysis for simultaneously possible and mutually exclusive interactions.

It has been shown that two such homodimers assemble using distinct, mutually exclusive interaction faces [18].

CoIP experiments in a mouse fibroblast cell line also revealed mutually exclusive interaction of CBX7 and RYBP with RING1B/MEL-18, indicathat that RYBP-PRC1 and CBX-PRC1 coexist in different cell types.

In addition to these biological roles, the mutually exclusive interaction between genes that program cell death (mcrBC) and an invading methyltransferase gene may give host cells an advantage in defence against viral infection when the virus carries a methyltransferase gene.

A dense cluster detected by the traditional methods by blindly treating all protein-protein interactions in the PPI network to be able to occur simultaneously may be a false prediction as it may contain several mutually-exclusive interactions.

This alternative representation of PPI networks provides a theoretical framework to model the evolution of the combinatorial logic underlying PPI networks, as it distinguishes mutually exclusive, direct interactions ("XOR") between protein domains (Fig. 4A, black solid lines) from cummulative, indirect interactions ("AND") within multi-protein complexes (Fig. 4A, red dashed lines).