Sentence examples for mutually exclusive dna from inspiring English sources
The rational functions for regulation involving both activator and repressor represent the competition between formations of two mutually exclusive DNA loops.
Epigenetic pathways regulate gene transcription by two different mechanisms that are not mutually exclusive: DNA methylation and post-translational modification of histones.
One such modification, H3K4me3, appears to be mutually exclusive with DNA methylation and therefore may be a candidate DNA methylation-blocking histone modification [54].
Because methylated H3K27 is independent of and potentially mutually exclusive with DNA methylation, this mark is not very informative for understanding the relationship among chromatin modifications, DNA methylation and gene regulation at this locus.
Further, H3K27me3 seems to occur mutually exclusive to DNA methylation and promote de novo silencing of genes in different cancers [6,111].
Epigenetic processes are not mutually exclusive to DNA-based inheritance, but may initially buffer phenotypes and populations in the face of new environmental challenges before genetic assimilation of altered phenotypes (Waddington 1942).
Another interesting observation of our study is the absence of a mutually exclusive pattern of DNA methylation changes within FEM modules.
Although not mutually exclusive, sequence-specific DNA binding factors also presumably re-recruit histone modifiers to the chromatin to re-establish histone modification patterns.
One possibility is that trimethylation of lysine 4 of histone 3 (H3K4) deposited at an active promoter prevents methylation, as a mutually exclusive distribution of DNA methylation and H3K4 methylation has been reported in genomewide studies in mammals [ 39] and this histone modification is unable to bind de novo DNMTs [ 40].
We establish that a second Dna2-Rpa interaction is mutually exclusive with Rpa-DNA interactions and mediates the displacement of Rpa from ssDNA.
Finally, to show that there is indeed a difference in the level of mutually exclusive patterns exhibited by DNA methylation and copy number, we compared the average path length distance of top-ranked differentially methylated genes to top-ranked amplified/deleted genes, using the TCGA data for which both DNA methylation and Affy SNP data is available.
