Exact(14)
Interaction of the receptor-ligand complex with Trg activates the cytoplasmically-localized histidine kinase (EnvZ) through the mutually conserved HAMP domain [8].
These hotspots were defined by the localization of at least three non-homologous insertions between mutually conserved core genes.
The structural alignment step allows very distantly related templates to be recognized, while the use of profile profile sequence comparison highlights the residue pairs that are mutually conserved.
This excludes all riboswitches found to be mutually conserved in all compared chromosomes, strengthening a hypothesis implicating cis acting RNA regulation as an ancient mechanism [ 36].
This tree shows distances between strains based on small adaptations inside mutually conserved genes, which translate into an approximate timeline when assuming consistent rates of evolution.
Also, CBP was first identified because of its capacity to bind CREB, but p300 also has this ability, for which they both use their mutually conserved KIX domain.
Similar(46)
The same is true for the region downstream of C4 (after the mutually very conserved TRP at pos. 184 in VibH coordinates) where a moderately conserved motif LPxDxxRP is seen in LCL which is completely absent in DCL (see Additional file 3).
The classification included one of 3 mutually exclusive degrees of conservation, in order of decreasing importance: 1) overlap with a UCSC Most Conserved segment, 2) conservation score >0.7, and 3) conservation score >0.3.
For example, FNR and FLP are conserved in a mutually exclusive manner (supplementary fig. S7, Supplementary Material online).
For example, in insects, mutually exclusive exons are as conserved as constitutive ones, and tolerate even less intron insertions than the latter [ 11].
Interestingly, H3K4 and H3K9 methylation levels are mutually exclusive, and this relationship is conserved from yeast to humans.
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