Sentence examples for mutually altered from inspiring English sources

The swap is then any mutually altered order of homologous regions in proteins, while the circular permutation refers to a special case of a swap where swapped regions cover essentially the whole protein length.

MEMo automatically identifies mutually exclusive alterations targeting frequently altered genes that are likely to belong to the same pathway.

Of major clinical significance was the observation that genes related to RTK/RAS signalling are frequently altered and mutually exclusive to one another in gastric cancer.

It is also interesting that the expression of genes for G protein α subunits 6 (gpaF) and 9 (gpaI) were altered in mutually opposite directions.

In the present study, we are only able to provide indirect evidence that RfBP+ and nfxl1 plants mutually counteract in altering cytosolic H2O2 concentrations and in the subsequent effects on flowering time and expression of FD and AP1 at the shoot apex.

To date there has been two mutually exclusive hypotheses regarding the altered PUFA composition observed in AE patients [56].

The transmission process is based on a Susceptible-Infective-Recovered (SIR) model where susceptible individuals may adopt two mutually exclusive behaviors, "normal" and "altered", on the basis of the perceived risk of infection.

Our results demonstrate that there exist pairs (A, B) of genes that are altered in a mutually exclusive manner across tumours.

Such cliques of drivers, suspect of producing the same set of downstream changes have been identified using algorithms that take advantage of their trend to be altered in a mutually exclusive manner across tumor samples [ 6– 8].

To explore the role of these alterations in a pathway context, we used the MEMo algorithm [ 31], which identifies micro-pathways or modules whose components are frequently altered in a mutually exclusive manner.

Although previous works have identified cliques of drivers altered in a mutually exclusive manner across tumor samples [ 7, 8] – under the same rationale that this pattern signals convergent roads to tumorigenesis – no study to date has directly tested the hypothesis that alterations in connected drivers actually result in the misregulation of similar sets of targets.