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As such, the mutual regulation between transcription factors and microRNAs regulate the bistable state between progenitor maintenance and myeloid development, where repression of inhibitory miRNA by histone demethylation of its promoter is associated with macrophage differentiation.
In conclusion, we have revealed mutual regulation between the tumor suppressor PTEN and the microRNA miR-22.
Accumulating evidence demonstrates a mutual regulation between EPH receptors and E-cadherin-based cell-cell adhesion.
For instance, mutual regulation between FASN and the growth factor-dependent signalling is suggested.
These interactions suggest the possibility of mutual regulation between PML and its interacting partners [ 23– 25].
This leads to the idea that there is a mutual regulation between cooperative TFs at levels of cooperativity higher than cooperative pairs.
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By constantly updating, EpimiR will become a more comprehensive and user-friendly database about mutual regulations between epigenetics and miRNA from high-throughput method identification and low-throughput experiment validation.
Mutual regulation is strongest between intimate pairs, but human beings regulate each other collectively as well.
Our results indicate that tph-1 and daf-7 are likely to act in parallel to modulate lifespan in response to food, and that their mutual regulation represents crosstalk between these two pathways.
However, even in these cases mutual regulation is required.
Cellular and neuritic morphology is modulated through mutual regulation of the actin and microtubule cytoskeleton.
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