Sentence examples for mutations with two from inspiring English sources

All but four are mis-sense mutations, with two mutations affecting splice sites, another creating an in-frame deletion, and one creating a premature stop codon.

We also simulated PAC detection of recurrent mutations with two breast cancer cell lines, of which HCC1937 had skipped RB1 exon 22, and we were already able to identify the mutant from among two samples up to even five mutants from among six samples (Fig. 4B).

Notice that the standard test w·ar - a·r compares two genotypes having zero and two mutations with two others each having one mutation.

This motif is critical because mutations with two Ts and two Gs substantially decrease its ability to bind to hnRNP I, providing further evidence of the specific interaction between hnRNP I and UCA1.

Twelve isolates possessed IS 6110-mediated mutations, with two of these also displaying indels involving presumably recombination-mediated swapping of parts of the 5' untranslated regions of PPE38 and PPE71.

The difference between the groups showed a trend toward reduced mutations with three versus two drugs but did not reach significance (P=.11, two-sided chi2).

As our goal was to produce highly stable variants of the growth factor, we combined these two mutations with five previously described stabilizing substitutions.

Thus, the data presented here provide guidance for designing of gRNA and donor DNA to do genome editing, especially to correct the mutations with three mismatched nucleotides, such as three-nucleotide deletion or insertion.

The third lesion (M3) exhibited 3 mtDNA mutations with one overlapping mutation with M2 (and917C) and M1 (G8836C) (Fig. 2A C, matched color).

Determining CNAs and mutations with one single sequencing effort renders our method very efficient in terms of time and money.

We analysed 99 hMLH1 and hMSH2 missense mutations with six different algorithms.