Sentence examples for mutations with only from inspiring English sources

The largest known study to date used only 31 proteins (101 mutations) with only 3 cases of disorder-to-order transitions65.

However, Mirny and his colleagues suspected that the evolutionary process in cancer can proceed differently, allowing mutations with only a slightly harmful effect to accumulate.

It is observed that when mutations with only a small stabilizing effect were combined with the disulfide bridge engineered into α helix, a considerable increase in thermostability was achieved.

Second, polymorphism in the open reading frame results in an excess of non synonymous over synonymous mutations, with only two synonymous mutations observed for 15 non synonymous mutations between the two most divergent alleles [16].

There was also a lack of variation in the frequency of molecular mutations with only 2 sites having frequencies of the dhfr/dhps quintuple mutation above 4%, and all sites with a high frequency of the dhps double mutation also had a high frequency of the dhfr triple mutation.

Most HPSE2 mutations in UFS are predicted to be null mutations, with only one missense mutation reported to date (10).

In conclusion, we successfully identified the causative mutation for a very rare autosomal recessive mutation with only one case by exploiting the most recent DNA sequencing technologies.

The lack of a potent role for p53 immediately following Apc loss also provides a ready explanation for the association of p53 mutation with only the later stages of colorectal disease [ 1].

As the virus spread between the animals by physical contact, it picked up additional mutations until, with only five mutations to differentiate it from the wild virus, it became airborne and able to spread via the kind of tiny droplets produced in a cough or sneeze.

For Pfdhfr-ts 69% of the isolates were mutated, with only three mutations detected (N51I, C59R, N108S) (Fig. 2B).

Across all tumor types, missense mutations were by far the most dominant category, with a smaller proportion of frame shift alterations and nonsense mutations and with only a very small proportion of indels (insertions/deletions).