Sentence examples for mutations with low from inspiring English sources
Confirming the simulation results, the entropy analysis was insensitive to mutations with low prevalence (<4 5%).
Ultimately, the cumulative contribution of such mutations with low effect sizes may play a large role in causing the disease.
Over 24% of mutations with low levels of aggression affect 'localization'; no mutations with high levels of aggression affect localization.
However, most mutations in PDGFRA are missense mutations with low mutation scores, offsetting the effect of low mutation rate to the test statistics of PDGFRA.
That said there is some evidence that resistance mutations with low or no fitness costs can be prevalent in clinical populations.
For the tomato, this LD pattern could be due to recent mutations with low frequencies (more than 50% of polymorphisms had MAF < 0.2).
Although limited by haematological toxicity, the use of higher doses of IV GCV (up to 10 mg/kg twice daily) [ 15] is a good option and makes sense in patients with UL97 mutations with low-grade resistance [ 18] or in mild-to-moderate disease.
In summary, TWSG1-deficient mice represent a genetic mouse model of a mutation with low penetrance that sensitizes embryos to environmental influences.
As expected, given the association of STAG2 mutation with low tumour grade and stage, we also found significant association with these other mutational events in the non-invasive tumour group.
In a study that examined a larger proportion of Ta tumours (65.5% Ta, 11.5% Ta, 23% T2), a significant association of mutation with low grade and stage was found [ 24], though overall frequency was lower (13%).
Briefly, BRCA1 loss through mutation is defined as germline or somatic mutation with low level of BRCA1 RNA and less than 1% nuclei positive for BRCA1 by immunohistochemistry. Cases with epigenetic BRCA1 loss show ≥4% fully methylated molecules, low level of BRCA1 RNA and less than 1% nuclei positive for BRCA1 in immunohistochemistry, with no BRCA1 or BRCA2 mutations.
