Sentence examples for mutations with increased from inspiring English sources

In this study, we screened a library of P. aeruginosa mutant bacteria in SP-A null and sufficient mice for mutations with increased susceptibility to pulmonary clearance by SP-A.

The SIFT algorithm relies upon evolutionary conservation to find mutations that have the greatest potential for negative functional impact and B-SIFT uses the same idea to find mutations with increased fitness.

While it is not possible to generalize because of differences in both species and cell type, it is intriguing that the association of germ line point mutations with increased cell division is in complete agreement with our results of point mutations in somatic cells being highly dependent on cell proliferation whilst rearrangements can occur in both dividing and non-dividing cell populations.

Digitalization of the DiOC stained image and counting DiOC stained ovule cells will allow us to develop protocols to identify cotton germplasms and mutations with increased density of fibers and follow the trait as it is crossed into elite germplasms.

Averages across many tissue types in the CCLE were used rather than matched expression measurements from TCGA since the pattern of decreased mutations with increased expression was more stable within mutation type, and because this same set of expression data could be used in studies of a different cancer or in studies where expression data was not available.

However, the sequential accumulation of mutations with increasing subculture time indicates that mutations also occur during the culture process as previously reported (Kaeppler et al. 2000).

Pham and colleagues reported similar findings: decreasing incidence of EGFR TK mutations with increasing pack years [39].

Those that do accumulate mutations with increasing passages as they adapt to the artificial environment they are cultivated in.

Our model is agnostic to sequence and protein structure but nevertheless associates branches containing these mutations with increasing fitness.

However, the specificity of errors created by replicative (pol α, pol δ), repair (pol β), or specialized (pol κ) DNA polymerases cannot readily explain the directionality bias toward expansion mutations with increasing allele length that was observed in human cells.

Several studies have reported associations of germline mutations in CHEK2, especially the 1100delC mutation, with increased susceptibility to breast and prostate cancer [ 3- 8].